Influence of gallogen and diethanolamine upon induced hypercholesterolemia in the rat.
نویسنده
چکیده
The diethanolamine salt of the mono (a,p-dimethylbenzyl) ester of d-caniphorie acid (Gallogen) augmented diet-induced hypercholesterolemia and hyperlipemia in the rat, while depressing liver cholesterol and total lipid concentrations. Diethanolamine had virtually identical effects. Gallogen, given orally to rats with biliary fistulas had a slight hydrocholeretic effect, but did not influence biliary excretion of cholesterol, cholic acid, or ehenodeoxycholic acid.
منابع مشابه
Influence of Gallogen and Diethanolamine Upon Induced Hypercholesterolemia in the Rat
The diethanolamine salt of the mono (a,p-dimethylbenzyl) ester of d-caniphorie acid (Gallogen) augmented diet-induced hypercholesterolemia and hyperlipemia in the rat, while depressing liver cholesterol and total lipid concentrations. Diethanolamine had virtually identical effects. Gallogen, given orally to rats with biliary fistulas had a slight hydrocholeretic effect, but did not influence bi...
متن کاملSEYMOUR DAYTON Influence of Gallogen and Diethanolamine Upon Induced Hypercholesterolemia in the Rat
Influence of Gallogen and Diethanolamine Upon Induced Hypercholesterolemia in the Rat Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 1958 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.6.3.271 1958;6:271-274 Circ Res. http://circres.ahajournals.org/...
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The influence of glycosaminoglycans (GAG) on collagen fibrillogenesis in vitro was investigated. GAG and collagen were isolated from the liver of rats treated with carbon tetrachloride at various time intervals (3-16 weeks). It was found that GAG obtained from the fibrotic liver accelerated collagen fibril formation. This effect was more evident in a solution of type I collagen than type II...
متن کاملThe hypocholesterolizing effect of gallogen and its potentiation by soybean sterols.
THE purpose of this communication is to report on the value of Gallogen* alone and in combination with soybean sterol in the treatment of experimentally induced atherosclerosis. Peterson and co-workers observed that the addition of soybean sterols to the diet of chicks, on a high fat-high cholesterol diet, lowers cholesterol levels in blood and liver more than when the soybean sterols were omit...
متن کاملDiethanolamine Manuscript
Diethanolamine increased the incidence and multiplicity of liver tumors in the mouse following chronic exposure. Diethanolamine is known to inhibit cellular choline uptake. Since choline deficiency produces tumors in rodents, diethanolamine, through choline depletion, may result in tumor development in rodents. The potential for diethanolamine to function through this mode of action in humans i...
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ورودعنوان ژورنال:
- Circulation research
دوره 6 3 شماره
صفحات -
تاریخ انتشار 1958